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   medchemexpress on March 17, 2014 at 11:11 pm

   Gatifloxacin side effects caused concern
   <a href=”http://www.medchemexpress.com/Gatifloxacin.html">Gatifloxacin</a> is a broad-spectrum fluoroquinolone antibiotic drugs in recent years developed a new antibiotic . But since 1999, the drug has been approved for listing the world how patients taking gatifloxacin in patients with symptoms of hypoglycemia and hyperglycemia . The researchers began to notice last year that the drug caused health problems, especially changes in glucose metabolism .
   Gatifloxacin in 1999 by the U.S. Food and Drug Administration (FDA) approved for listing in April 2002 in Japan approved for listing . Gatifloxacin for the treatment of pneumonia, bronchitis and urinary tract , kidney , skin, and other infectious diseases , and generally for the treatment of gonorrhea , and urinary tract infection in the lungs . Doctors often in the nature of the infection is not very clear circumstances to prescribe this drug ,<a href=”http://www.medchemexpress.com/Gatifloxacin-hydrochloride.html">Gatifloxacin hydrochloride</a> the main consideration of its wider antibacterial spectrum . However, in clinical use, found that the drug can lead to changes in glucose metabolism , and changes in blood sugar can cause coma and other serious problems , even death. Patients with symptoms usually begin within 5 to 10 days after taking the drug .
   According to the U.S. “Los Angeles Times ” Web site on March 2 , entitled ” Antibiotics may cause elderly glucose ,” the article reads : Elderly patients taking the widely used antibiotic gatifloxacin (Gatifloxacin) can cause elevated blood sugar, may be hospitalized resistance will increase nearly 16 -fold ; this drug can also cause lower blood sugar , increase the likelihood of patients hospitalized three times .<a href=”http://www.medchemexpress.com/Gatifloxacin-mesylate.html">Gatifloxacin mesylate</a> This conclusion on the cause of some doctors recommend this drug will be withdrawn from the market .
   “New England Journal of Medicine” website published a research report this year showed that: the patients taking the drug 1% of hospitalization . Several previous studies have shown that diabetes increases the risk of blood sugar abnormalities occur after taking this antibiotic , also appeared several deaths. This latest study suggests that all patients taking the drug are at risk , not even in patients with diabetes as well. Authors of the study said, because other antibiotics have the same effect, there is no reason to continue using this drug.
   U.S. drug manufacturer Bristol-Myers Squibb Company also said: The study concluded that ” after-sales experience to date is consistent with our ” so that they take into account when applying changes to the specification of these conclusions .
   February 16 ,<a href=”http://www.medchemexpress.com/Clotrimazole.html">Clotrimazole</a> the official FDA website message : add a new contraindication in gatifloxacin TEQUIN (Gatifloxacin) SmPC : diabetes drug may cause side effects, increased patient symptoms of hypoglycemia or hyperglycemia risks, this may result in premature aging , degradation of renal function , diabetes disabled.
   March , Health Canada and Bristol-Myers Squibb Company jointly issued the relevant gatifloxacin safety alert bulletins.
   And there are four of these drugs similar to fluoroquinolones , some of which have been withdrawn from the market or severely restricted , respectively temafloxacin (Temaflloxacin), grepafloxacin (Grepafloxacin), sparfloxacin (Sparfloxacin ) and Qu difloxacin (Trovafloxacin).
   May 12 , FDA website “Drug shortages bar” in the release of the Bristol-Myers Squibb Company announced VincentJ.Bilinsky vice president of trade on the Canadian market gatifloxacin termination statement . <a href=”http://www.medchemexpress.com/Meropenem.html">Meropenem</a>The statement to consumers , said: The company decided to terminate TEQUIN Paradox (Gatifloxacin) plus gatifloxacin tablets for business behavior and injection , based on global trends in the U.S. market structure and commercial considerations and the antibiotic products , as well as restructuring the company strategy the company will from June 2 to stop the supply of drugs to the U.S. pharmaceutical wholesalers.
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